Filtered for Longevity & Reliability

Biodemographic (Reliability) Theory of Aging and Longevity

The quest for general theory of aging and longevity has become an important part of biodemographic studies (Carey & Judge, 2001). In this paper we suggest to include the reliability theory in the theoretical arsenal of biodemographic research for developing a comprehensive theory of aging and longevity. Reliability theory is a general theory about systems failure. It allows researchers to predi...

The reliability theory of aging and longevity.

Reliability theory is a general theory about systems failure. It allows researchers to predict the age-related failure kinetics for a system of given architecture (reliability structure) and given reliability of its components. Reliability theory predicts that even those systems that are entirely composed of non-aging elements (with a constant failure rate) will nevertheless deteriorate (fail m...

Reliability Theory of Aging and Longevity

Filtered compression for Kappa

Kappa is a language geared towards the modelling of the complex systems of reactions that can occur between proteins inside cells. It is supported by sophisticated simulation and static analysis techniques which can be applied to the models to study their emergent behaviour. Part of this is the construction by the simulator of causal histories explaining the generation of patterns of connectivi...

Aging and Total Quality Management: Extending the Reliability Metaphor for Longevity

Reliability models of longevity can be usefully extended in several directions. In particular, rather than simply optimizing parameters within a structure that is tightly defined a priori, it may be more illuminating to examine interactions between highand low-level design decisions, by analogy with the engineering principle of ”Total Quality Management.” The sources of decay are more various a...